PCD = Prof. Peter Dedon
SRT = Prof. Steven Tannenbaum
Course calendar.
| LEC # |
TOPICS |
LECTURERS |
KEY DATES |
| 1 |
Introduction and Principles |
PCD |
|
| 2 |
Chemistry/Biochemistry Review |
|
|
| 3 |
Overview of Drug Development |
Guest: Dr. Robert Rubin |
Homework 1 due |
| 4 |
Uptake/Transport/Distribution of Drugs |
PCD |
|
| 5 |
Drug Transporters |
Guest: Dr. Keith Hoffmaster |
Homework 2 due |
| 6 |
Bioethics Seminar |
|
|
| 7 |
Drug Transporters (cont.) |
Guest: Dr. Keith Hoffmaster |
|
| 8 |
Introduction to Drug Metabolism |
SRT |
|
| 9 |
Liver Lecture |
|
Project teams assigned |
| 10 |
Drug Metabolism 2 |
SRT |
|
| 11 |
Drug Metabolism 3 |
Guest: Dr. Sean Harriman |
|
| 12 |
Drug Metabolism 4 |
Guest: Dr. Sean Harriman |
|
| 13 |
Quiz Review |
|
Homework 3 due one day after Lec #13 |
|
Quiz 1 |
SRT |
|
| 14 |
Oxygen Radicals in Drug Toxicity |
SRT |
|
| 15 |
Drug Toxicities |
SRT |
|
| 16 |
Drug Toxicities (cont.) |
SRT |
|
| 17 |
Bioethics Seminar |
|
|
| 18 |
Pharmacokinetics |
PCD |
Project summaries due
Homework 4 due |
| 19 |
Pharmacokinetics (cont.) |
PCD |
Homework 5 due |
| 20 |
Receptors and Case Study - Omeprazole |
PCD |
|
| 21 |
Case Study - Omeprazole |
PCD |
|
| 22 |
Case Study - Omeprazole (cont.) |
PCD |
|
| 23 |
Case Study - Acetaminophen |
SRT |
|
| 24 |
Case Study - Acetaminophen (cont.) |
SRT |
|
| 25 |
Case Study - Statins |
SRT/PCD |
Presentation schedule ready |
| 26 |
Case Study - Statins (cont.) |
SRT/PCD |
Papers due |
| 27 |
Drug Industry Seminar |
Guest: Mark Trusheim (Massachusetts Biotech Council) |
|
| 28 |
Case Study - Statins (cont.) |
SRT/PCD |
|
| 29 |
Student Presentations |
|
|
| 30 |
Quiz Review |
|
|
| 31 |
Student Presentations (cont.) |
|
|
|
Quiz 2 |
|
|